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Combining G with other substances increases risks and unpredictability. Some combinations can overwhelm the body, especially when depressants are involved.
Common Drug Interactions:
| Substance | Effect When Mixed with GHB/GBL |
|---|---|
| Alcohol | Severe sedation, vomiting, blackouts, and breathing problems |
| Benzodiazepines (e.g. Xanax) | Increased risk of coma, overdose, and death |
| Stimulants (e.g. meth, cocaine) | Unpredictable reactions, body strain, heart complications |
| HIV meds (e.g. ritonavir, cobicistat) | May increase GHB/GBL toxicity due to CYP enzyme interactions |
Always know what’s in your system. If you’re taking medication or other substances, avoid layering G unless you’ve had a conversation with a trusted medical professional.
Disclaimer: This post is intended to provide information on s for harm reduction purpose. It does not advocate for or promote the use of any illicit substances
